Delar i serien Linköping Univer Similarly, a regulatory effect of estradiol and tamoxifen on endostatin generation was observed in normal human breast tissue by whole-tissue culture and microdialysis in human breast tissue in situ. Sahlgrenska Academy Department of Radiation Physics. Start Expand Start Minimize Start. In the female reproductive organs, sex steroids regulate angiogenesis and MMP activity, yet little is known how sex steroids affect these crucial events in normal and malignant breast tissue.
In conclusion, the results presented in this thesis suggest previously unknown mechanisms of action of estradiol and tamoxifen in breast cancer and in normal human breast tissue, and novel means by which estradiol may tip the scale to favor angiogenesis.
Av lärosätet Linköpings universitet. Delar i serien Linköping Univer Radiation Physics and Radiobiology: The basic science laboratory is located at the Sahlgrenska Cancer Center. Samverkan Expand Samverkan Minimize Samverkan. Sök utanför SwePub Sök vidare i: The group has produced a total of 31 doctoral theses over the years and trained a number of endocrine surgeons, surgical pathologists and medical physicists.